Pharmaceutical Crystallography: The Ultimate Guide to Structure and Analysis
Welcome to the fascinating world of pharmaceutical crystallography, where the structure and properties of crystalline drug substances are meticulously analyzed and optimized. This comprehensive guide is your gateway to unlocking the secrets of pharmaceutical crystallography, empowering you with the knowledge and techniques to delve deeper into this highly specialized field.
4.4 out of 5
Language | : | English |
Text-to-Speech | : | Enabled |
Enhanced typesetting | : | Enabled |
Word Wise | : | Enabled |
Print length | : | 305 pages |
File size | : | 4159 KB |
Screen Reader | : | Supported |
Chapter 1: The Fundamentals of Crystallography
Embark on an in-depth journey into the fundamentals of crystallography, exploring the basic concepts and principles that govern the formation and properties of crystals. Discover the various crystal systems, lattice types, and symmetry operations that shape the structural diversity of crystalline materials.
Chapter 2: X-Ray Diffraction: A Window into Crystal Structure
Delve into the realm of X-ray diffraction, the primary technique employed to determine the crystal structure of pharmaceutical compounds. Uncover the principles behind X-ray diffraction, unraveling the secrets of how X-rays interact with crystals to reveal their structural details.
Chapter 3: Crystal Analysis and Structure Refinement
Master the art of crystal analysis and structure refinement, the meticulous process of interpreting X-ray diffraction data to derive the precise atomic arrangement within a crystal. Explore techniques such as structure solution methods, electron density mapping, and least-squares refinement, gaining a deep understanding of how crystal structures are determined.
Chapter 4: Polymorphism and Crystal Engineering
Uncover the fascinating world of polymorphism, where the same pharmaceutical compound can exist in multiple crystal forms with distinct structures and properties. Delve into the principles of crystal engineering, learning how to design and manipulate crystal structures to optimize drug performance.
Chapter 5: Pharmaceutical Applications and Case Studies
Witness the practical applications of pharmaceutical crystallography in the development and optimization of drug substances. Study real-world case studies that showcase how crystallography has revolutionized the pharmaceutical industry, improving drug stability, solubility, and bioavailability.
This Pharmaceutical Crystallography Guide To Structure And Analysis is your indispensable companion in the realm of crystallography. It equips you with a deep understanding of the principles, techniques, and applications of pharmaceutical crystallography, empowering you to make groundbreaking contributions to drug discovery and development. Embrace the power of crystallography and unlock the secrets of pharmaceutical compounds, paving the way for safer, more effective, and innovative therapies.
4.4 out of 5
Language | : | English |
Text-to-Speech | : | Enabled |
Enhanced typesetting | : | Enabled |
Word Wise | : | Enabled |
Print length | : | 305 pages |
File size | : | 4159 KB |
Screen Reader | : | Supported |
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4.4 out of 5
Language | : | English |
Text-to-Speech | : | Enabled |
Enhanced typesetting | : | Enabled |
Word Wise | : | Enabled |
Print length | : | 305 pages |
File size | : | 4159 KB |
Screen Reader | : | Supported |